FIGURE

Figure 5

ID

ZDB-FIG-190723-1488

Publication

Zhu et al., 2019 - Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish via Toxic Gain of Function

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Figure 5

The ahi1 knockout (KO) line ahi1lri^46−/−embryos exhibited no significant difference from WT in optic nerve projection length and eyes size. (A) The ahi1lri^46−/− zebrafish has depleted most of the region of the ahi1 gene and only retains the N-terminal coiled-coil domain. (B) Fluorescent images of WT and ahi1lri^46−/−zebrafish optic nerve projections at 4 dpf. Scale bar: 200 μm. (C) The quantified optic nerve projection length and eye sizes of WT and ahi1lri^46−/− embryos. (D) The two-dimensional scatter diagram for the eye size of WT and ahi1lri^46−/− embryos; the X-axis represents the length of optic nerve projection (μm²), and the Y-axis represents the size of eyes (μm²). ns, not significant. Error bars denote SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ahi1^lri46/lri46
Observed In:	eye retinal ganglion cell axon retinal ganglion cell axon guidance
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.