FIGURE

Fig. 9

ID

ZDB-FIG-190722-22

Publication

Hayward et al., 2019 - Glucococorticoid receptor activation exacerbates aminoglycoside-induced damage to the zebrafish lateral line

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Fig. 9

Glucocorticoid transcriptional activity is localized in hair cells. (Red = HCs labeled with anti-parvalbumin (parv). Green = GFP (with signal enhanced by anti-GFP), indicative of GR transcriptional activity). (A) Glucocorticoid transcriptional activity occurs in some hair cells of untreated fish (GFP+/parv+, white arrow). (B) Glucocorticoid transcriptional activity occurs in many hair cells of cortisol-treated fish (GFP+/parv+, white arrows), and in supporting cells (GFP+/parv-, white arrowhead). Scale bar = 10 μm and applies to all panels. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Hearing Research, 377, Hayward, T., Young, A., Jiang, A., Crespi, E.J., Coffin, A.B., Glucococorticoid receptor activation exacerbates aminoglycoside-induced damage to the zebrafish lateral line, 12-23, Copyright (2019) with permission from Elsevier. Full text @ Hear. Res.