FIGURE
Fig. 5
- ID
- ZDB-FIG-190626-52
- Publication
- Chopra et al., 2019 - Zebrafish duox mutations provide a model for human congenital hypothyroidism
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Fig. 5
Homozygous duox mutations lead to goitre. Adult mutant animals exhibit an array of variably sized external goitres (arrowheads; A,B), as well as lateral flaring of opercula (arrowheads; C). When sectioned along the length of the follicular region (dotted area, D) and subjected to ISH for thyroglobulin, mutants reveal extensive spread of and ectopic thyroid follicular tissue (G–L), in contrast to the localised, discreet distribution in WT and heterozygous siblings (arrowheads; E,F). Scale bars: 1 mm. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage: | Adult |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Adult |
Phenotype Detail
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