FIGURE

Fig. 2

ID

ZDB-FIG-190606-34

Publication

Patowary et al., 2019 - Family-based exome sequencing and case-control analysis implicate CEP41 as an ASD gene

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Fig. 2

Analysis of migration of CNC cells in the control MO (a–c), cep41 MO (d–f), P206A (g–i) and cep41 MO+ zebrafish cep41 mRNA (j–l)-injected zebrafish at 8, 10 and 12 somite stages. Asterisks, red arrows and white arrows indicate migrating CNC cells in the forebrain, midbrain and hindbrain, respectively. The extent of medial expansion of CNC cells (yellow arrows, zoomed in area) was compared in the hindbrain of each zebrafish (c′, f′, i′, l′). m. All data are representative of at least five independent experiments. The quantified data of zebrafish with defective CNC cell migration are graphically presented (20 embryos/counting). Abnormal: either delayed migration or medial expansion of CNC cells

Expression Data

Antibody:	Ab7-sox10
Fish:	AB AB + MO1-cep41
Knockdown Reagent:	MO1-cep41
Anatomical Terms:	migratory cranial neural crest neural crest
Stage Range:	5-9 somites to 10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-cep41
Knockdown Reagent:	MO1-cep41
Observed In:	cranial neural crest cell cell migration hindbrain migratory cranial neural crest cell migratory cranial neural crest
Stage Range:	5-9 somites to 10-13 somites

Phenotype Detail

Acknowledgments

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