FIGURE

Fig. 6

ID

ZDB-FIG-180712-69

Publication

Kidwell et al., 2018 - Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum

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Fig. 6

atoh1c^fh367 cerebellar cells accumulate as post-mitotic but undifferentiated granule cell progenitors. A,B: The majority of Tg(atoh1c::kaede)+ cells (green) in the atoh1c mutant are located within the URL and do not express HuC/D (red) at 5 dpf (B) indicating that they are not post-mitotic neurons. C,D: atoh1c^fh367 cells (green) in the URL are positive for NeuroD1 (red, D). E,F: atoh1c^fh367 cells (green) in the URL do not incorporate EdU (red, F). Strong EdU incorporation anterior to the cerebellum in both wild-type and mutant is in the optic tectum (OT). Dorsal views with anterior to the left. Scale bars: 50 μM.

Expression Data

Gene:	Kaede
Antibodies:	Ab1-elavl Ab1-neurod
Fish:	fh430Tg; s1999tTg atoh1c^fh367/fh367; fh430Tg; s1999tTg
Anatomical Terms:	medial caudal lobe cerebellar granule cell rhombomere 1 antero-dorsal region
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atoh1c^fh367/fh367; fh430Tg; s1999tTg
Observed In:	cerebellar granule cell differentiation rhombomere 1 antero-dorsal region
Stage:	Day 5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 438(1), Kidwell, C.U., Su, C.Y., Hibi, M., Moens, C.B., Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum, 44-56, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.