FIGURE

Fig. 4

ID

ZDB-FIG-180403-37

Publication

Furlan et al., 2017 - Life-Long Neurogenic Activity of Individual Neural Stem Cells and Continuous Growth Establish an Outside-In Architecture in the Teleost Pallium

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Continuous Neurogenesis from the Pallial her4-Positive RG Population

Top: experimental design. Distribution of mCherry-positive neurons (A–F) born from RGs that were her4 positive at the time of 4OHT induction (stages at the bottom right of each panel). Cross-sections at 3 mpf are at identical mid-antero-posterior levels and the level is indicated by a red line on telencephalon dorsal view (A′–F′: mCherry and DAPI staining). Red lines indicate boundaries between territories with mCherry-positive and -negative neuronal cell bodies (mCherry is cytoplasmic in the ubi:switch line [3535], and thus also stains processes). White lines indicate pallial-subpallial boundaries. Green lines delimit the recombined (Dm, medial part of Dl) and un-recombined (lateral part of Dl, Dp) pallial territories in her4^switch animals treated with 4OHT (see [2121]; at any given time point, all pallial RGs are her4 positive [Figure S2Figure S2]; however, the pallial VZ expands laterally over time through the addition of RGs originating from a her4-negative source; therefore, the green lines shift toward the lateral with later recombination times). The her4^switch fish in (F) and (F′) was subjected to two consecutive inductions, at 1 dpf (medial neurons only, left to green bar limit) and then at 1.5 mpf (superficial neurons, right to green bar limit). Scale bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Curr. Biol.