FIGURE

Fig. 7

ID

ZDB-FIG-180103-29

Publication

Lu et al., 2017 - Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy

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Fig. 7

Photoreceptor OS proteins were mislocalised in EYS^−/− zebrafish.

(A) Retinal cryosections from WT and EYS^−/− zebrafish were immunostained with anti-opn1LW antibodies at 10 dpf. White arrows indicated the mislocalised opn1LW proteins. Scale bars: 10 μm. (B) Retinal cryosections from WT and EYS^−/− zebrafish were immunostained with anti-opn1SW1 antibodies at 10 dpf. White arrows indicated the mislocalised opn1SW1 proteins. Scale bars: 10 μm. (C) Retinal cryosections from WT and EYS^−/− zebrafish were immunostained with anti-GNB3 antibodies at the age of 5 mpf. White arrows indicate the mislocalised GNB3 proteins. Scale bars: 50 μm. (D) Retinal cryosections from WT and EYS^−/− zebrafish were immunostained with anti-PRPH2 antibodies at the age of 7 mpf. White arrows indicated the mislocalised PRPH2 proteins. Scale bars: 50 μm.

Expression Data

Antibodies:	Ab1-gnb3 Ab1-prph2 Ab2-opn1lw Ab2-opn1sw2
Fish:	WT eys^hzu4/hzu4
Anatomical Terms:	retina photoreceptor inner segment retina photoreceptor outer segment
Stage Range:	Days 7-13 to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	eys^hzu4/hzu4
Observed In:	retina photoreceptor inner segment
Stage Range:	Days 7-13 to Adult

Phenotype Detail

Acknowledgments

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