FIGURE

Fig. 1

ID

ZDB-FIG-171004-8

Publication

Demy et al., 2017 - Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues

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Fig. 1

Moonshine mutants and Trim33 morphants are devoid of microglia. (A–F) In vivo dorsal view of Neutral Red-stained primitive microglia in the midbrain optic tectum of 3-day-old moonshine^NQ039/Tü siblings (Sib) (A) and mutants (Mut) (B), moonshine^TB222/Tü siblings (C) and mutants (D), and of the siblings (E) and mutants (F) resulting from their complementation cross. (G) Corresponding counts (Nb, number) of Neutral Red-positive (NR+) microglial cells in the midbrain optic tectum of moonshine mutants and siblings, and of Trim33 morphants versus control uninjected embryos. Each dot is one embryo. Error bars show mean±s.e.m. KD, knockdown; Mo, morphant; mon, moonshine; Tü, wild-type Tübingen strain. ***P<0.001; ns, not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	trim33^{t30813/t30813} (TU) trim33^{tb222b/tb222b} (TU) TU + MO4-trim33
Knockdown Reagent:	MO4-trim33
Observed In:	microglial cell optic tectum
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.