FIGURE

Fig. 5

ID

ZDB-FIG-170925-13

Publication

He et al., 2017 - Insm1a Is Required for Zebrafish Posterior Lateral Line Development.

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Fig. 5

Insm1a regulates the expression of chemokine signaling components. WISH was used to detect the expression of cxcl12a (A,B), cxcr4b (C,D), and cxcr7b (F,G) in control and insm1a morphants at 30–32 hpf. (E,H) The ratio of cxcr4b-positive cells (E) or cxcr7b-positive cells (H) to total cells in the primordia of controls (black bars) and insm1a morphants (gray bars). Data are expressed as mean ± s.e.m. *p < 0.05; ***p < 0.001. The cxcl12a expression is reduced in insm1a morphants, while cxcr4b expression is up-regulated and cxcr7b expression is down-regulated in insm1a morphants compared to controls. The primordium is outlined with a dotted line, and the anterior is to the left. Scale bar: 50 μm (A,B) and 10 μm (C–F).

Expression Data

Genes:	ackr3b cxcl12a cxcr4b
Fish:	WT WT + MO4-tp53 + MO5-insm1a
Knockdown Reagents:	MO4-tp53 MO5-insm1a
Anatomical Terms:	myoseptum posterior lateral line primordium
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO4-tp53 + MO5-insm1a
Knockdown Reagents:	MO4-tp53 MO5-insm1a
Observed In:	myoseptum posterior lateral line primordium
Stage:	Prim-15

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.