FIGURE

Fig. 6

ID

ZDB-FIG-170501-4

Publication

Seberg et al., 2017 - TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF

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Fig. 6

Forced expression of tfap2a does not rescue melanocytes in mitfa mutant zebrafish.

(A-D) Nuclei of melanocytes expressing mosaic Tg(mitfa:tfap2a-Myc) are brightly labeled after anti-Myc immunostaining. At 48 hpf, labeled melanocytes in mitfa^z25/z25 mutant embryos (A, B) and mitfa^w2/z25 mutant embryos (C, D) display no apparent improvement in pigmentation or dendricity compared to adjacent unlabeled cells (B and D, white arrowheads). (E, F) In mitfa^w2/w2 mutants, all labeled cells are unpigmented and resemble other cell types including xanthophores (F, white arrowhead).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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