FIGURE

Fig. 4

ID

ZDB-FIG-170303-16

Publication

Kuri et al., 2017 - A high-sensitivity, bi-directional reporter to monitor NF-κB activity in cell culture and zebrafish in real-time

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Fig. 4

Dynamic NF-κB activity during early zebrafish embryonic development. (A–E) Light-sheet images of Tg(8×Hs.NFκB:GFP,Luciferase) embryos show ubiquitous, weak NF-κB activity from 6 hpf until 12 hpf. (F) The first strong tissue-specific signal was observed in the nasal vesicle (nv) at around 16 hpf. (G–K) Confocal images of Tg(8×Hs.NFκB:GFP,Luciferase) embryos from 1 dpf until 5 dpf. GFP was detected in the proctodeum (p) at 1 dpf (G). The GFP signal in the nasal vesicle (G) originates from microvillous sensory neurons (H). E–G and I–K show embryos in lateral view. Anterior is to the left. H shows the head of embryos from the frontal side. Yellow arrows indicate GFP in the lateral line. White arrowheads indicate GFP in the intestine. Scale bars: 100 µm (A–F); 300 µm (G); 50 µm (H); 500 µm (I–K).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.