Fig. 8
- ID
- ZDB-FIG-160819-48
- Publication
- Dupret et al., 2016 - The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging
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Phenotype of 12 month-old pcgf1-/- mutants. (A) Pictures of 12 month-old pcgf1+/+ and pcgf1-/- fish. Note that both male and female pcgf1-/- fish exhibit mild spinal curvature. (B) Measurements of the spinal curvature score in 12 month-old fish from the pcgf1+/+ and pcgf1-/- populations. Statistical significance was assessed by Student t-test analysis and significance expressed as the value of p. (C) Senescence-associated β-galactosidase (SA-β-Gal) activity in 12 month-old zebrafish. Whole body staining of SA-β-Gal activity in pcgf1+/+ and pcgf1-/- fish harboring a spinal curvature are compared. (D) Quantification of SA-β-Gal activity in pcgf1+/+ and pcgf1-/- fish. Blue pixels obtained by whole body staining of SA-β-Gal activity were quantified in the trunk area between the operculum and the dorsal and anal fins by Adobe Photoshop and plotted using Prism (GraphPad). Error bars indicate ± SD. |
Fish: | |
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Observed In: | |
Stage: | Adult |