FIGURE

Fig. S7

ID

ZDB-FIG-160601-8

Publication

Yang et al., 2016 - A genetic mechanism for convergent skin lightening during recent human evolution

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Fig. S7

Effect of zebrafish oca2 knockdown on melanophore pigmentation. A:Test of oca2-MO effectiveness. Injection of poca2-EGFP plasmid DNA at the one-cell stage resulted gave rise to GFP during mid gastrulation, which was effectively blocked by co-injection of oca2-MO. B: Effect of oca2 knockdown on pigmentation. One-cell stage embryos were injected with 5 ng or 10 ng oca2-MO and observed for pigmentation at 36 or 48 hpf. The ratio of embryos with the representative pigmentation level was indicated. Note that embryos injected with 5 ng oca2-MO showed variable levels of pigment reduction in contrast to complete loss of pigmentation in embryos injected with 10 ng oca2-MO.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU + MO1-oca2
Knockdown Reagent:	MO1-oca2
Observed In:	pigmentation whole organism
Stage Range:	Prim-25 to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol Bio Evol