FIGURE

Fig. 3

ID

ZDB-FIG-160211-10

Publication

Shen et al., 2015 - RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study

Other Figures

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Fig. 3

Cytological analysis of Tg(RE:HSE:EGFP) zebrafish. Cytology of hematopoietic cells from WT (a) and Tg(RE:HSE:EGFP) F2 generation (b) zebrafish at 60 dpf. The blood cells from WT fish were predominantly erythrocytes, and by contrast, erythrocytes were significantly inhibited in Tg(RE:HSE:EGFP) fish, enriched for abundant blast-like cells, which are larger than the erythrocytes and have high nuclear to cytoplasmic ratios, containing multiple large nucleoli (black arrow). These blasts were similar to that of human AML peripheral blood. The similar feature presented in single cell suspensions of kidneys from WT (c) and Tg F2 generation (d)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf685Tg
Observed In:	blood nucleate erythrocyte blood cell
Stage:	Days 45-89

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Cancer