FIGURE

Fig. 1

ID

ZDB-FIG-151208-23

Publication

Li et al., 2015 - Immobilization of Dystrophin and Laminin α2-Chain Deficient Zebrafish Larvae In Vivo Prevents the Development of Muscular Dystrophy

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Fig. 1

Early immobilization by BTS prevents muscle structural changes in Sapje (Sap) mutant larvae and their normal siblings (Sib) at 4 dpf.

Upper panels: birefringence microscopy of Sap and siblings from 0.1% DMSO and 50 µM BTS treatment respectively. Lower panels: whole mount preparations with Rhodamine phalloidin staining. Arrows indicate altered areas. These illustrations were typical of n = 6 Rhodamine phalloidin stained samples per each group, in 3 treatment sets. Scale bars: 1 mm (upper); 50 µm (lower).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT dmd^{ta222a/ta222a}
Condition:	chemical treatment: toluene-4-sulfonamide
Observed In:	skeletal muscle skeletal muscle cell
Stage:	Day 4

Phenotype Detail

Acknowledgments

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