FIGURE

Fig. 2

ID

ZDB-FIG-150616-26

Publication

Zhang et al., 2015 - Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine

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Fig. 2

Morphology and larval locomotor activity of scn1Lab ATG morphants in comparison to control larvae with non-inflated swim bladder.

(A) Dorsal view of a representative 5-dpf CTRL MO-injected larva with non-inflated swim bladder (NISB CTRL MO). (B) The y-axis depicts the total larval locomotor activity of ATG MO- compared to CTRL MO-injected larvae and CTRL MO-injected larvae win non-inflated swim bladder (NISB CTRL MO) over a one-hour tracking experiment (30-minute integration time). Data were analyzed from one experiment with 8–12 larvae per injection condition. Statistical analysis was performed using Dunnett′s multiple comparisons test. Error bars on all graphs represent standard error of mean (SEM). * P d 0.05, ** P d 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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