FIGURE

Fig. S1

ID

ZDB-FIG-150518-8

Publication

Oltrabella et al., 2015 - The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule

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Fig. S1

Dextran uptake assay and colocalization with endosomes.

A. Schematic representation of pronephric tubules (green) in 72hpf zebrafish embryos (left lateral view, top right dorsal view) (top) and pronephric uptake assay in 72hpf zebrafish embryos (bottom) showing embryos immediately after injecting Alexa 488-10 kDa dextran (10kDa-FD, green)(left) or after 2.5h incubation to allow accumulation in the pronephros (arrow) (right). B. Confocal transverse section of zebrafish proximal pronephric tubule of 72 hpf zebrafish embryos injected with Alexa 488-10 kDa dextran (green) and incubated for 2.5 h prior to fixation and labelling with antibodies to the early endosome marker EEA1 (red). Scale bar, 5 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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