FIGURE

Fig. 3

ID

ZDB-FIG-150413-3

Publication

Banerjee et al., 2015 - Zebrafish foxc1a drives appendage-specific neural circuit development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

foxc1a is required for fin-innervating motor nerves to convert at the plexus. (A) Lateral (composite) view of a 96-hpf-old Tg(mnx1:GFP) larvae expressing GFP in all motor nerves. Yellow dashed boxes mark anterior segments (AS) and posterior segments (PS) considered in this study; white dotted area outlines the pectoral fin. (B,C) Compared with wild-type larvae, trunk innervation (posterior segments) is unaffected in foxc1a mutants. (D-G) By contrast, three out of the four fin-innervating nerves in foxc1a mutants display axonal defects at 48hpf (D-G) and at 96hpf (H-K). Dotted areas outline the pectoral fin, arrowheads indicate the position of the fin plexus and arrows indicate the fourth pectoral fin nerve. Cyan asterisks indicate ectopic fasciculation; red asterisks mark defasciculation. Scale bars: 50µm.

Expression Data

Gene:	GFP
Fish:	ml2Tg foxc1a^p162/p162; ml2Tg
Anatomical Terms:	motor neuron motor neuron axon pectoral fin motor nerve pectoral fin motor nerve axon pectoral fin motor nerve 1 pectoral fin motor nerve 1 axon pectoral fin motor nerve 2 pectoral fin motor nerve 2 axon pectoral fin motor nerve 3 pectoral fin motor nerve 3 axon pectoral fin motor nerve 4 pectoral fin motor nerve 4 axon
Stage Range:	Long-pec to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	foxc1a^p162/p162; ml2Tg
Observed In:	pectoral fin motor nerve 1 motor neuron axon guidance pectoral fin motor nerve 2 axon pectoral fin motor nerve 2 axon terminus pectoral fin motor nerve 2 motor neuron axon guidance pectoral fin motor nerve 3 axon pectoral fin motor nerve 3 axon terminus pectoral fin motor nerve 3 motor neuron axon guidance pectoral fin motor nerve 4 motor neuron axon guidance pectoral fin nerve axon terminus
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development