FIGURE
Fig. 10
- ID
- ZDB-FIG-140923-34
- Publication
- Lin et al., 2014 - Hypoxia-Inducible Factor 2 Alpha Is Essential for Hepatic Outgrowth and Functions via the Regulation of leg1 Transcription in the Zebrafish Embryo
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Fig. 10
The small liver phenotype caused by hif2-alpha knockdown can be rescued by ectopic leg1 expression. The expression pattern of the lfabp gene was examined in Tg(lfabp:EGFP) embryos (A) and compared with hif2-alpha ATG-MO-injected embryos (8 ng) (B) as well as embryos co-injected with hif2-alpha ATG-MO (8 ng) and leg1 cRNA (C). (D) lfabp mRNA expression was detected by qPCR in wild-type embryos and compared with hif2-alpha ATG-MO-injected embryos, hif2-alpha ATG-MO and leg1 cRNA co-injected embryos, as well as hif2-alpha ATG-MO and hif2-alpha cRNA co-injected embryos. Expression was normalized to β-actin. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Terms: | |
| Stage: | Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
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