FIGURE

Fig. 1

ID

ZDB-FIG-140903-37

Publication

Schiavone et al., 2014 - Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer

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Fig. 1

Tissue specificity expression of eGFP and eGFP-KRAS^G12D under control of ptf1a promoter and Kaplan–Meier analysis. (A,B) Lateral views, anterior to the right showing that EGFP (A) and eGFP-KRAS^G12D (B) are specifically expressed in cerebellum (red arrows) and pancreas (white arrows) of larvae observed at 5 dpf. (C) Kaplan–Meier analysis of dead or severely sick animals revealed lethality for about 92% of Tg(ptf1a:Gal4)/UAS:eGFP-KRAS^G12D as measured at 24 wpf. Differences between Tg(ptf1a:eGFP) and Tg(ptf1a:Gal4)/UAS:eGFP-KRAS^G12D were statistically significant with P<0.05. Number of sample for each group are indicated.

Expression Data

Gene:	EGFP
Fish:	jh1Tg/jh1Tg
Anatomical Terms:	cerebellum pancreas
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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