FIGURE

Fig. 2

ID

ZDB-FIG-140304-12

Publication

Xu et al., 2014 - Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function

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Fig. 2

Swap70 morphants exhibiting reduced length of the body axis can be rescued by ectopic expression of GFP/Swap70b fusion protein. (A) Zebrafish embryos were either un-injected (WT) or injected with GFP/swap70b mRNA (150 pg), swap70b MO1 (2.5 ng, 5 ng) or co-injected with GFP/swap70b mRNA (150 pg) and swap70b MO1 (5 ng). Swap70 morphants at 24 hpf were grouped according to the severity of their morphological phenotypes into normal (blue), mild (green), moderate (pink) and severe (red). Images of representative embryos are shown. (B) Quantification of the phenotypic analysis. n: total number of embryos derived from at least three independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO4-swap70b
Knockdown Reagent:	MO4-swap70b
Observed In:	embryo development whole organism whole organism anterior-posterior axis
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 386(1), Xu, X., Shuen, W.H., Chen, C., Goudevenou, K., Jones, P., and Sablitzky, F., Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function, 191-203, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.