FIGURE

Fig. 7

ID

ZDB-FIG-131213-43

Publication

Warga et al., 2013 - Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity

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Fig. 7

Fgf and Wnt signaling activity are elevated in spt mutants. (A–C) Expression at 10 and 12 h of: (A) spry4, (B) il17rd, and (C) spry2. All 10 h embryos are shown in a dorsal posterior view, the 12 h embryos in (C) are shown in left side view. Designations: arrow, tailbud (10 h) or posterior mesoderm (12 h); open arrowhead, Kupfer′s vesicle; asterisk, paraxial mesoderm; and arrowheads, midbrain-hindbrain boundary region and rhombomere 4. (D) Expression at 7 h of β-catenin protein seen at high magnification in ventral marginal cells. Cells in the mutant (right), are not as cohesive with one another as in wildtype and make abnormal intercellular contacts and gaps. They also appear to have higher cytoplasmic and nuclear staining.

Expression Data

Genes:	il17rd spry2 spry4
Fish:	WT tbx16^b104/b104
Anatomical Terms:	forerunner cell group midbrain hindbrain boundary neural plate paraxial mesoderm presumptive rhombomere 4 tail bud
Stage Range:	Bud to 5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 383(1), Warga, R.M., Mueller, R.L., Ho, R.K., and Kane, D.A., Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity, 75-89, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.