FIGURE

Fig. 8

ID
ZDB-FIG-130619-29
Publication
Nair et al., 2013 - The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo
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Fig. 8

Birc5b localizes to cortical microtubule tips and co-localizes with F-actin and germ plasm RNPs.

High magnifications of animal views of blastodisc cortex. In wild-type embryos, Birc5b (B, L) localizes to monoaster microtubule tips (A, C, K, M, arrows) and polymerizing F-actin (D, E). In motley/birc5b mutants (F–J) Birc5b co-localizes with polymerizing F-actin (I, J), but as tips of the microtubules are not seen at the cortex (F), co-localization to the microtubule tip is not observed. Birc5b at the microtubule tips (K, M arrow) co-localizes with GP RNPs in wild-type embryos (N, O). In motley/birc5b mutants (P–T), microtubule tips are not seen at the cortex (P) but Birc5b continues to localize with GP RNPs (S, T).

Expression Data
Gene:
Antibodies:
Fish:
Anatomical Terms:
Stage: 1-cell

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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