FIGURE

Fig. S4

ID

ZDB-FIG-130618-37

Publication

Yao et al., 2013 - Anaplastic lymphoma kinase is required for neurogenesis in the developing central nervous system of zebrafish

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Fig. S4

Proliferation and differentiation in the alk:HSE:cfp² line. (A,B) Confocal sections of 24hpf embryos of the alk:HSE:cfp² line. Sib (A) and Tg+ (B) had different neural tube shapes. Dividing cells (pH 3, green) and neurons (HuC/D, red) in Tg+ embryos (B) were both mispositioned (arrowhead), identical to defects observed in the alk:HSE:cfp¹ line (Fig. 2). Asterisk labels 4^th ventricle. (C,C′,D,D′) Ectopic pERK (arrows) in Tg+ (D,D′) of the alk:HSE:cfp² line compared to Sib (C,C2), identical to defects observed in alk:HSE:cfp¹ (Fig. 3). pERK, phosphorylated-ERK1/2. Sib, transgene negative siblings. Tg+, transgenic embryos. Scale bars: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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