FIGURE

Fig. 2

ID

ZDB-FIG-130320-6

Publication

Sainath et al., 2013 - Plexin a3 and turnout regulate motor axonal branch morphogenesis in zebrafish

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Fig. 2

turnout controls guidance and branching of primary motor axons.

(A, C, E) 24 hpf wild-type embryos injected with mnx1:GFP to visualize individual CaP, MiP and RoP motor neurons, and counter-stained with the SV2 antibody (red) to visualize the segmental exit points (asterisks). (B) A turnout CaP motor neuron projecting rostrally within the spinal cord, and exiting from an adjacent hemisegments midsegmental exit point. (D) A MiP motor neuron failing to migrate upon exit from the spinal cord. (F) A RoP motor axon projecting rostrally and exiting from an adjacent hemisegment exit. (G, H) turnout CaP and RoP motor neurons with correct axonal trajectories and ectopic branches. Dashed line indicates somite boundary. Scale bar, 10 µm.

Expression Data

Antibody:	Ab-SV2
Fish:	WT tot^{p5THBD/p5THBD}
Anatomical Term:	motor neuron axon
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	tot^{p5THBD/p5THBD}
Observed In:	axon extension involved in axon guidance CaP motoneuron axon CaP motoneuron axon collateral CaP motoneuron cell body collateral sprouting in absence of injury MiP motor neuron axon MiP motor neuron cell body RoP motor neuron axon RoP motor neuron axon collateral RoP motor neuron cell body
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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