FIGURE

Fig. 4

ID

ZDB-FIG-130124-14

Publication

Carra et al., 2012 - Ve-ptp Modulates Vascular Integrity by Promoting Adherens Junction Maturation

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Fig. 4

The zve-ptp MOb injection caused an increase in vascular permeability.

(A–D) Microangiographies were performed on tg(fli1:EGFP)^y1 embryos at 2 dpf by the injection of dextran-TMR (tetramethylrhodamine; molecular weight 70 kDa). All microinjected embryos presented blood circulation. Confocal images of tail vessels of std-MO (A, C) and MOb injected embryos (B, D) at t1 = 10 minutes (A, B) and t2 = 15 minutes (C, D). (E, F) Merge of the images at t2 of embryos injected with std-MO and MOb with the respective images of the tail vessels obtained using tg(fli1:EGFP)^y1 line. (A2–F2 A3–F3) Higher magnifications of the respective boxed areas. Asterisks: dye extravasation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO2-ptprb
Knockdown Reagent:	MO2-ptprb
Observed In:	caudal vein dorsal longitudinal anastomotic vessel
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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