FIGURE

Fig. 6

ID

ZDB-FIG-120717-9

Publication

Ulrich et al., 2011 - Neurovascular development in the embryonic zebrafish hindbrain

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

SU5416 treatments reveal stage-specific VEGF signaling requirements for BA and CtA development. A-N, Maximum intensity confocal projections of immuno-fluorescently stained embryos carrying the endothelial reporters Tg(kdrl:ras-mCherry)^s896 and Tg(kdrl:nls-GFP). Endothelium, red. Endothelial cell nuclei, green. Images show 36 (A-F) and 48 hpf (G-N) embryos treated with 0.01% of the drug vehicle DMSO (control) or with 1 μMof the VEGF signaling inhibitor SU5416 (in 0.01% DMSO) at the ages indicated in parentheses (26, 30 or 36 hpf). Abbreviations (see Table 1): vasculature, white (apostrophe, right side). Small white arrows, CtAs. A-C, G-J, Left lateral views. Anterior, left. Dorsal, up. D-F, K-N, Dorsal views. Anterior, left. Left side, bottom. Scale bar (A), 100 μm.

Expression Data

Genes:	EGFP mCherry
Fish:	s896Tg; ubs1Tg
Condition:	chemical treatment: semaxanib
Anatomical Terms:	endothelial cell membrane endothelial cell nucleus
Stage Range:	Prim-25 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 357(1), Ulrich, F., Ma, L.H., Baker, R.G., and Torres-Vazquez, J., Neurovascular development in the embryonic zebrafish hindbrain, 134-51, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.