Fig. 2
- ID
- ZDB-FIG-120426-23
- Publication
- Huang et al., 2012 - Novel expression patterns of metabotropic glutamate receptor 6 in the zebrafish nervous system
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RNA expression of zebrafish mglur6 and gnao paralogs. RNA expression of mglur6a (A1–A4), mglur6b (B1–B4), gnaoa (C1–C4) and gnaob (D1–D4) in dorsal (1) and lateral (2) views and in isolated eyes (3) of a 5 dpf zebrafish, as well as in adult retinal cross-sections (4). A1, A2: Expression of mglur6a is visible in the habenula (Ha), the medial (TeO) and lateral (lTeO) tectum opticum, the midbrain (mb), a part of the mid-hindbrain boundary (mhb) and a bilateral nucleus of the medulla oblongata (MO). A3: In an eye separated from a whole mount stained larva mglur6a is expressed in the proximal inner nuclear layer (INL, arrow) and the ganglion cell layer (GCL). A4: Additional to the cellular expression in the proximal INL (arrows) and the GCL, mglur6a labels cells in the medial INL (arrowheads) in adult. B1, B2: mglur6b reveals a staining in the olfactory bulb (OB) and a weak labeling of a part of the diencephalon (di). B3: The isolated eye shows, mglur6b expression in the medial INL (arrowhead), the proximal INL (arrow) and the GCL. B4: The adult retinal cross section shows the same localization for mglur6b as the larval fish, however, the staining in the medial INL is restricted to a subset of cells (arrowheads). C1, C2: gnaoa is expressed in the olfactory bulb (OB), the pallium (P), the habenula (Ha), the tectum opticum (TeO) and in all cranial ganglia (CG, arrowheads). C3: The retina reveals gnaoa labeling in the proximal INL (arrow) and the GCL. C4: Similar to the larval retina, gnaoa labels the proximal INL (arrow) and the GCL in the adult retina. Additionally, gnaoa stains weakly a subset of cells in the medial INL (arrowheads). D1, D2: gnaob shows no expression in the brain. D3: The expression of gnaob in the larval fish eye is restricted to the medial INL (arrow) and the GCL. D4: Similar to the larval eye, in adult retinal cross-sections gnaob is located in cells of the medial INL and the GCL. All scale bars = 40 μm. Scale bar in A1 applies to all whole mount images, scale bar in A3 applies to A3, B3, C3 and D3, scale bar in A4 applies to A4, B4, C4 and D4. |