FIGURE

Fig. 9

ID

ZDB-FIG-120405-51

Publication

Cavaco Rodrigues et al., 2012 - Skeletal muscle regeneration in Xenopus tadpoles and zebrafish larvae

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Fig. 9

Zebrafish larvae show no muscle dedifferentiation phenotype. Micrographs from semithin sections showed that larval tail myofibres have a well organized sarcomeric structure that do not show signs of dedifferentiation during regeneration (arrows). (a, b) At 0 dpa and 1 dpa, distal most fibres show altered sarcomeric striations, characteristic of damaged or dying myofibre (arrowheads). (c) At 3 dpa this phenotype was not observed (neither at 2 dpa, not shown), instead, less muscle is observed close to the amputation plane (asterisk). (d) At 6 dpa, new myofibres are visible in the regenerate (left arrow). Notochord (N) is visible as an oval at 3 and 6 dpa because of the slight dorsal curvature that regenerating tails acquire (see Figure 8h). Dashed lines: amputation planes. n e four sections per animal, three animals per time point.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.