FIGURE

Fig. S5

ID

ZDB-FIG-120202-55

Publication

Dohn et al., 2012 - Distinct phases of Wnt/β-catenin signaling direct cardiomyocyte formation in zebrafish

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Fig. S5

Expression of a dominant-negative TCF at the TB stage does not increase the size of the heart. (A,C) HCSEs. (B,D) Hearts from GFP + Tg(hsp70l:Δtcf3-GFP)^w26 embryos heat-shocked at the TB and 16 s stages. (B) Although morphology was more linear when ΔTCF-GFP was induced at the TB stage, the hearts did not appear larger. However, at the TB stage overexpression of ΔTCF-GFP causes a significant amount of cell death in embryos (not shown), potentially precluding analysis. (D) Heart from transgenic embryo when ΔTCF-GFP is induced at 16 s. All images are frontal views at 48 hpf. Red indicates ventricles and green indicates atria.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 361(2), Dohn, T.E., and Waxman, J.S., Distinct phases of Wnt/β-catenin signaling direct cardiomyocyte formation in zebrafish, 364-76, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.