FIGURE

Fig. 4

ID

ZDB-FIG-111206-5

Publication

Lopez-Schier et al., 2006 - A two-step mechanism underlies the planar polarization of regenerating sensory hair cells

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Fig. 4

Characterization of hair-cell regeneration in several zebrafish mutant lines. (A–C) Gastrulation defects in zebrafish are associated with the silverblick/wnt11, pipetail/wnt5a, and knypek mutations (21–23). Labeling of neuromasts in 6-day-old larvae with rhodamine-phalloidin reveals that the hair bundles are properly orientated in pipetail (A), silberblick (B), and knypek mutant animals (C). (D) A neuromast of a trilobite mutant animal is included for comparison. The planar polarity defects of hair cells in trilobite mutants are associated with the loss of Vangl2 function specifically in neuromasts, rather than a consequence of gastrulation defects. (Scale bars: 10 μm.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA