FIGURE

Fig. 3

ID

ZDB-FIG-111115-10

Publication

Gutierrez et al., 2011 - Aberrant AKT activation drives well-differentiated liposarcoma

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

AKT pathway activation in primary human well-differentiated and dedifferentiated liposarcomas. (A–C) H&E staining of human lipoma, WDLPS, and DDLPS specimens. (D–F) Immunohistochemistry for Ser473-phosphorylated AKT in a representative lipoma and AKT-positive WDLPS and DDLPS clinical specimens. (Scale bar, 100 μm.) (G–I) Immunohistochemistry for phospho-S6 ribosomal protein (Ser235/236) in a representative lipoma, as well as AKT-positive WDLPS and DDLPS clinical specimens. (J and K) Quantitation of phospho-AKT and phospho-S6 immunohistochemistry in pure WDLPS, pure DDLPS, and in human tumors with mixed well-differentiated and dedifferentiated liposarcoma components.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA