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Fig. S5

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ZDB-FIG-111101-43

Publication

Deng et al., 2011 - Dual roles for Rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue

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Fig. S5

Figure S5. Rac2 D57N partially inhibited CXCR4-WHIM induced neutrophil clustering, related to Figure 6.

(A) Sudan black staining of neutrophil clusters at the ventral side of the head where SDF-1 is expressed in Tg(mpx:CXCR4-WHIM). Rac2 D57N expression in neutrophil partially inhibits this clustering.

(B) Confocal images of neutrophil distribution at the ventral side of the head in Tg(mpx:CXCR4-WHIM, mpx:mCherry-2A-Rac2 WT or D57N) at 3dpf. Green, CXCR4-GFP; red, Rac2-2A-mCherry. Scale bar, 30 μm.

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Acknowledgments

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Reprinted from Developmental Cell, 21(4), Deng, Q., Yoo, S.K., Cavnar, P.J., Green, J.M., and Huttenlocher, A., Dual roles for Rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue, 735-745, Copyright (2011) with permission from Elsevier. Full text @ Dev. Cell