Fig. 4
- ID
- ZDB-FIG-110929-21
- Publication
- Greenhill et al., 2011 - An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development
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Induction of Mitfa-responsive genes is largely suppressed by Sox10. Representative groups of wild-type embryos are shown after injection of mRNA as indicated to left (mitfa (A) and sox10, assayed at 6 hpf (B) or 10.5 hpf (C)), raised to stage indicated, then fixed and processed by in situ hybridisation to detect genes named above panels (purple). Arrowheads indicate specific signal above background levels. D) Data is quantified as percentage of injected embryos showing expression in graphs at right (n>44 in each case). |