FIGURE

Fig. 5

ID

ZDB-FIG-110622-42

Publication

Tsai et al., 2011 - The predominant protein arginine methyltransferase PRMT1 is critical for zebrafish convergence and extension during gastrulation

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Fig. 5

Defective phenotypes at segmentation stage for prmt1 morphants. (A) Dorsal view of embryos (10-somite stage) for krox20 staining. The positions of r3 and r5 are indicated. The widths of r3 and r5 and the vertical distance between r3 and r5 are indicated. In type 1 morphants, r3 was almost normal but r5 was slightly extended laterally. The width of r3 and r5 were extended to < 1.5-fold in type 2 and even to 2–2.5-fold in type 3. (B) Expression of myoD at paraxial/adaxial mesoderm at the 10-somite stage. Dorsal views, anterior at top. The lengths of myoD expressed paraxial/adaxial mesoderm are indicated. In type 1, 2 and 3 morphants, the length was < 0.8–0.9, 0.6–0.7 and 0.5 compared to normal. (C) The phenotypes were classified according the degree of abnormality as type 1, 2, and 3. Percentages of wild-type and morphants embryos within each phenotypic category are shown in the bar graphs. n, total embryos counted in the experiments.

Expression Data

Genes:	egr2b myod1
Fish:	WT WT + MO1-prmt1
Knockdown Reagent:	MO1-prmt1
Anatomical Terms:	adaxial cell rhombomere 3 rhombomere 5
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-prmt1
Knockdown Reagent:	MO1-prmt1
Observed In:	whole organism anterior-posterior axis
Stage:	10-13 somites

Phenotype Detail

Acknowledgments

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