Fig. 5
- ID
- ZDB-FIG-110318-32
- Publication
- Felber et al., 2011 - Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish
- Other Figures
- All Figure Page
- Back to All Figure Page
ptc1-/- fish have enhanced osteoblastogenesis. osx staining at 96 hpf of wild type (A and C), ptc1-/- (B) and ptc2-/- fish (D) reveals that ptc1-/- larvae have increased expression in the ceratohyal perichondrium and ptc2-/- fish have no change. Expression at achondral sites of ossification is unaffected. Alizarin red staining at 168 hpf of wild type (E and G), ptc1-/- (F) and ptc2-/- fish (H) shows that some of the ptc1-/- fish have increased perichondral ossification (7 out of 25 mutant fish) while ptc2-/- fish are indistinguishable from their siblings. ptc1-/- fish also have ectopic perichondral ossification (5/25) that bridges from the joint of the opercle to the hyomandibula (insets in E and F). Please see Fig. 2 for abbreviations and notes. |
Reprinted from Mechanisms of Development, 128(1-2), Felber, K., Croucher, P., and Roehl, H.H., Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish, 141-152, Copyright (2011) with permission from Elsevier. Full text @ Mech. Dev.