FIGURE

Fig. 3

ID
ZDB-FIG-101210-6
Publication
Sartori da Silva et al., 2010 - Essential Role for the d-Asb11 cul5 Box Domain for Proper Notch Signaling and Neural Cell Fate Decisions In Vivo
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Fig. 3

Cullin box domain promotes induction of hes1 gene in vitro.

nTera-d1 cells were co-transfected with hes1-luciferase (hes1) or hes1-luciferase lacking the conserved CSL-binding site (hes1-RBPdel) and myc-tag (MT) as a control, or myc-tagged d-asb11 full length (MT-Asb11) or myc-tagged asb11cul (MT-Asb11cul) cDNA. Hes1-dependent Notch activity was analyzed by luciferase measurement.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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