FIGURE

Fig. 5

ID

ZDB-FIG-100806-70

Publication

Pei et al., 2010 - A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3

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Fig. 5

Optic nerve deficits in opa3^ZM/ZM mutants. (A) Sections of opa3^+/+ and opa3^ZM/ZM adult retinas. Three 1-year-old adult fish for each genotype were coronally sectioned and Hematoxylin and Eosin stained. One representative section is shown for each genotype. White arrows indicate optic nerve diameters and measurement points. Arrowheads indicate optic nerve lesions. Black arrows indicate retinal ganglion cells. (B,C) Comparison of optic nerve diameters (B) and retinal ganglion cell numbers (C) in opa3^+/+ and opa3^ZM/ZM adult fish. Each dot represents a single measurement, horizontal lines show the average and vertical lines show the standard deviation. Red lines and data points are significantly different from black lines and data points (t-test, P<0.015).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	opa3^hg8Tg/hg8Tg
Observed In:	eye retinal ganglion cell optic nerve head
Stage:	Adult

Phenotype Detail

Acknowledgments

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