FIGURE

Fig. 4

ID

ZDB-FIG-100714-3

Publication

van der Sar et al., 2002 - Eye defects in receptor protein-tyrosine phosphatase alpha knock-down zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Defects in retinal organization and differentiation in receptor protein-tyrosine phosphatase alpha morpholino (RPTPα-mo) -injected embryos. A,B: Oblique section of 3-days-postfertilization (dpf) -old wild-type (wt) embryo labeled with polyclonal anti-RPTPα antibody (AP5478; A) and anti-acetylated tubulin (B). Labeling is found in the optic nerve (arrow 1), the inner plexiform layer (arrow 2), and the outer plexiform layer (arrow 3). C,D: Oblique section of 3-dpf-old RPTPα-mo–injected embryo labeled with polyclonal anti-RPTPα antibody (AP5478; C), and anti-acetylated tubulin (Actub) antibody (D). Labeling of RPTPα and acetylated tubulin is found in the optic nerve (arrow 1), all other structures labeled in wild-type are not labeled in RPTPα-mo–injected embryos.

Expression Data

Gene:	ptpra
Antibody:	Ab1-ptpra
Fish:	WT WT + MO2-ptpra
Knockdown Reagent:	MO2-ptpra
Anatomical Terms:	cranial nerve II retinal inner plexiform layer retinal outer plexiform layer
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-ptpra
Knockdown Reagent:	MO2-ptpra
Observed In:	cranial nerve II
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.