FIGURE
Fig. 4
- ID
- ZDB-FIG-100506-61
- Publication
- Sheng et al., 2010 - Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect
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Fig. 4
Analysis by acetylated tubulin staining of embryos at 6 dpf. Compared to the uninjected embryo, the WD40 deletion morphant has reduced and disorganized axon tracts in the midbrain of zebrafish. This phenotype could be rescued by over-expressing either zLRRK2 (WD40+zLRRK2) or hLRRK2 (WD40+hLRRK2) mRNA. **P<0.01, ***P<0.001 (unpaired Student′s t-test). |
Expression Data
| Antibody: | |
|---|---|
| Fish: | |
| Knockdown Reagents: | |
| Anatomical Term: | |
| Stage: | Day 6 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Day 6 |
Phenotype Detail
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