FIGURE

Fig. 3

ID

ZDB-FIG-091202-1

Publication

Pack et al., 1996 - Mutations affecting development of zebrafish digestive organs

Other Figures

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Fig. 3

Mutations affecting the developing zebrafish intestine. (A,C,E,G,I) Lateral views of living 5 dpf larvae. (B,D,F,H,J) Corresponding histological cross-sections through the mid-intestine. Lumen size varies with position along the anterior-posterior axis and with muscular contractions. (A,B) Wild type. The intestinal epithelium (arrow) is highly folded, bile is visible in the lumen and the gas bladder is inflated. The intestinal epithelium is polarized with basal nuclei and a microvillus brush border. (C,D) slj^m74, (E,F) m750, (G,H) sst^m311, (I,J) pie^m497. The intestinal wall of all mutants is thin, lacks folds and the epithelium is not fully polarized and shows signs of degeneration. Scale bar, B, F and H, 20 μm; D, 15 μm; J, 25 μm.

Expression Data

Gene:	ins
Antibodies:	Ab1-CPA Ab3-ins
Fish:	AB polr3b^m74/m74 (AB)
Anatomical Terms:	endocrine pancreas exocrine pancreas
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pie^m497/m497 (AB) polr3b^m74/m74 (AB) sst^m311/m311 (AB) unm_m750^m750/m750 (AB)
Observed In:	intestinal epithelium intestine
Stage:	Day 5

Phenotype Detail

Acknowledgments

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