FIGURE

Fig. 3

ID

ZDB-FIG-091007-4

Publication

Jacoby et al., 2009 - The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachment

Other Figures

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Fig. 3

Electron micrographs of the vertical myoseptum reveal a highly irregular MTJ in sof embryos. (A,B) At lower magnification (x10,400), the wild-type myoseptum is compact and linear (A) whereas the sof myoseptum appears severely distorted, even in the absence of fibre detachment (B). Numerous processes extending into the myotome are clearly visible in the mutant (B, arrows), and blisters within the myoseptum are also indicated (arrowheads). (C,D) At higher magnification (x62,400), the smooth, layered structure of the BM at the wild-type MTJ is evident (C). By contrast, the sof BM lacks organisation, with a rough surface (bracketed) and only patches of layering (arrowhead) (D).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	lamb2^{tm272a/tm272a}
Observed In:	vertical myoseptum vertical myoseptum basement membrane
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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