FIGURE

Fig. 3

ID

ZDB-FIG-090817-55

Publication

Sun et al., 2009 - Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Myocyte hypertrophy contributes to early stages of cardiac remodeling in tr265/tr265.

(A–B′) Images of cardiomyocytes (red⁺ blue⁺; arrow) and non-cardiomyocytes (blue⁺ only; arrowhead) in week-6 and -16 (A, B) sibling and (A′,B′) tr265/tr265 ventricle sections from fish outcrossed to Tg(cmlc2:nuDsRed) fish, whose terminally-differentiated cardiomyocyte nuclei are fluorescent red; blue is Hoechst-labeling of nuclei; bar = 10 μm. (C–D′) Dissociated ventricular cardiomyocytes cultured and imaged to reveal cell size and shape from week-6 and-16 (C,D) sibling and (C′,D′) tr265/tr265 fish; bar = 20 μm. (E) Cardiomyocyte and (F) non-cardiomyocyte density (cells/mm²) from fish represented in A–B′. (G) Surface area (in μm²) of cultured cardiomyocytes, like the ones in C–D′. (E–G) mean±SEM; * = P<0.05. n = number of fish examined.

Expression Data

Gene:	DsRed2
Fish:	slc4a1a^tr265/tr265; f2Tg
Anatomical Term:	cardiac muscle cell nucleus
Stage Range:	Days 30-44 to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	slc4a1a^tr265/tr265; f2Tg
Observed In:	cardiac muscle cell cardiac ventricle cardiac muscle cell
Stage Range:	Days 30-44 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One