FIGURE
Fig. 3
- ID
- ZDB-FIG-090602-10
- Publication
- Rothschild et al., 2009 - Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis
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Fig. 3
Tbx5 heart defects can be rescued by CaMK-II. Wild type or cmlc2:DsRed transgenic embryos (k–o) were injected with the mismatch MO (5 ng), camk2b2 MO (2 ng) or tbx5 MO (5 ng) with or without 40 pg wild type δC CaMK-II cDNA and imaged at 72 hpf (a–e; k–y) or subjected to cmlc2 in situ hybridization at 48 hpf (f–j). Scale bar = 0.5 mm and anterior is to the left. In f and k, a = atrium and v = ventricle. In p–t, insets reveal bmp4 in situ hybridization patterns in the pectoral fin area. In u–y, brackets indicate extent of pectoral fin length. |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Knockdown Reagents: | |
| Anatomical Terms: | |
| Stage Range: | Long-pec to Protruding-mouth |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 330(1), Rothschild, S.C., Easley, C.A. 4th, Francescatto, L., Lister, J.A., Garrity, D.M., and Tombes, R.M., Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis, 175-184, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.