FIGURE

Fig. 2

ID

ZDB-FIG-090224-40

Publication

Yang et al., 2009 - hnRNP I Inhibits Notch Signaling and Regulates Intestinal Epithelial Homeostasis in the Zebrafish

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Fig. 2

brom bones has significantly reduced number of intestinal goblet cells.

(A,B) PAS-AB staining shows the intestinal goblet cells (arrowheads in A) in the anterior intestines of brom bones heterozygous fish (A) and homozygous fish (B). (C,D) The enzymatic activity of intestinal alkaline phosphatase (AP) in the enterocytes brush border (arrows) of the anterior intestines in brom bones heterozygous fish (C) and homozygous fish (D). (E) Quantification of the goblet cell number. Values shown are the percentages of goblet cells relative to the total number of intestinal epithelial cells per villous cross-section (n = 129 villi from 7 brom bones heterozygous fish and 154 villi from 9 brom bones homozygous fish). Error bars represent s.e.m; P = 1x10^-6 by Student's t test. Scale bar = 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ptbp1a^{p50ada/p50ada} (AB) ptbp1a^{p50ada/p50ada} (TU)
Observed In:	intestinal bulb epithelium goblet cell intestinal epithelial structure maintenance
Stage:	Adult

Phenotype Detail

Acknowledgments

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