FIGURE

Fig. 6

ID

ZDB-FIG-090112-19

Publication

Yoshinari et al., 2009 - Gene expression and functional analysis of zebrafish larval fin fold regeneration

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Fig. 6

Genetic mutations affecting the larval fin fold regeneration. (A, B) Disrupted larval fin fold regeneration in hspa9 mutants. The larval regeneration was apparently impaired (severe defect in 44/56 mutants, mild defect in 8/56 mutants; (A), whereas the uncut mutants did not show such defects (B). (C, D) Disrupted larval fin fold regeneration in yng/smarca4 mutants. A complete penetrance of defect in regeneration was observed in yng/smarca4 mutants (n = 28/28 mutants, C). Despite the mutant phenotypes such as smaller eyes and curved body axis, hspa9 and yng/smarca4 mutants were alive at 5 dpf and retain a good cellular viability. (E, F) Normal regeneration in other mutants. Several other mutants including you mutants, which have a defect in hedgehog signaling (Kawakami et al., 2005), did not display such defects (n = 15, E). The same magnifications for panels A–F (scale bar in panel A).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hspa9^{hi3366Tg/hi3366Tg} smarca4a^a8/a8 Df(Chr13:klhdc3,lclat1,npas4l,slc30a10)m39/m39
Observed In:	fin regeneration
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 325(1), Yoshinari, N., Ishida, T., Kudo, A., and Kawakami, A., Gene expression and functional analysis of zebrafish larval fin fold regeneration, 71-81, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.