FIGURE

Fig. 7

ID

ZDB-FIG-081003-44

Publication

Wang et al., 2008 - Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish

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Fig. 7

Phenotypes of atp1b2b morphant fish (72 hpf). (A) Otic vesicles from wild-type embryos contained two otoliths (arrowheads). (B,C) atp1b2b morphant fish lacked one (B) or both (asterisk, C) otoliths and had ventral protuberances due to pericardial effusion (arrows), consistent with cardiac failure. (D) atp1b2b morphant neuromasts had significantly fewer hair cells than wild-type embryos. (E) Cardiac ventricular chamber sizes were smaller and contractile cycle length was longer (corresponding to slower heart rate) in atp1b2b morphant fish compared with wild-type fish. SSAx, systolic short axis; DSAx, diastolic short axis; CL, cycle length.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-atp1b2b
Knockdown Reagent:	MO3-atp1b2b
Observed In:	cardiac ventricle heart contraction inner ear morphogenesis otic vesicle otolith pericardium posterior lateral line neuromast neuromast hair cell startle response
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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