enz selectively affects chromatophores among neural crest derivatives. Wild-type (A, C, E, G) and enz (B, D, F, H) mutant embryos. Craniofacial cartilages revealed with alcian blue staining are normal at 5 dpf (A, B: ventral view). Cervical sympathetic neurons, which express TH immunoreactivity (arrowheads in C, D), are indistinguishable between wild-type (C) and enz mutant (D) embryos at 7 dpf. (E–H) Hu-positive neurons of the dorsal root ganglia (E, F, arrowheads) and the enteric nervous system (arrowheads in G, H) also appear normal in enz mutant embryos (F, H) compared to wild-type siblings (E, G) at 7 dpf.
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