FIGURE

Fig. 7

ID

ZDB-FIG-080505-22

Publication

Matthews et al., 2008 - Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA

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Fig. 7

Interaction between Syn4 and PCP signaling. Zebrafish genetic interaction experiment. Lateral views of dorsal neural tubes of 20-somite zebrafish embryos are shown after crestin staining by in situ hybridization. Dorsal to the top; anterior to the left. (A) Wild-type embryo. (B) Wild-type embryo injected with 1 ng of syn4 MO. (C) tri mutant. (D) tri mutant injected with 1 ng of syn4 MO. (E) Percentage of inhibition of NC migration. White, no inhibition; yellow, mild inhibition; red, strong inhibition. (F) Wild-type embryo injected with 1 ng of wnt5 MO. (G) Wild-type embryo co-injected with 1 ng of wnt5 MO and 1 ng of syn4 MO. (H) Percentage of inhibition of trunk NC migration.

Expression Data

Gene:	crestin
Fish:	WT vangl2^{unspecified/unspecified} WT + MO1-sdc4 WT + MO1-wnt5b vangl2^{unspecified/unspecified} + MO1-sdc4 WT + MO1-sdc4 + MO1-wnt5b
Knockdown Reagents:	MO1-sdc4 MO1-wnt5b
Anatomical Term:	neural crest
Stage:	20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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