FIGURE
Fig. S5
- ID
- ZDB-FIG-080326-81
- Publication
- Schonthaler et al., 2008 - The zebrafish mutant lbk/vam6 resembles human multi-systemic disorders caused by aberrant trafficking of endosomal vesicles
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Fig. S5
Skin melanocytes are hypopigmented in lbk. Skin melanocytes in wild-type (A,B) and lbk mutant larvae (C,D) at 5 dpf. (B,D) Higher magnifications of regions in A and C, respectively. Melanosome number is substantially reduced in the lbk melanocytes (C), which leads to the hypopigmentation characteristic of these mutants, and the abnormally shaped melanosomes (D, arrowheads). Despite a majority of abnormally small and misshapen melanosomes, lbk skin melanocytes contain some melanosomes displaying wild-type size, shape and levels of melanin pigmentation (arrow). Scale bars: 5 μm in A,C; 1 μm in B,D. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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